Mapping one dose and two dose COVID vaccine efficacy for virus variants: Data to inform policy decisions

The last month saw three timelines overlap: global recognition of SARS-CoV-2 “variants”, worsening of the pandemic, and COVID-19 vaccine authorizations in many nations. As a result, policy decisions have been made regarding use of two doses of vaccine at varying intervals, and discussion of using only one dose in order to vaccinate as many people as possible now.

Urgent data to inform policy decisions should include a roadmap of the percent vaccine efficacy for each vaccine against the predominant international virus (D614G), the initial three variants and more that will surely follow.